Mark Pimentel Selected Research

cytolethal distending toxin

10/2020	Immunization with cytolethal distending toxin B produces autoantibodies to vinculin and small bowel bacterial changes in a rat model of postinfectious irritable bowel syndrome.
1/2020	Microbiome and Its Role in Irritable Bowel Syndrome.
1/2017	Assessment of Anti-vinculin and Anti-cytolethal Distending Toxin B Antibodies in Subtypes of Irritable Bowel Syndrome.
5/2015	Autoimmunity Links Vinculin to the Pathophysiology of Chronic Functional Bowel Changes Following Campylobacter jejuni Infection in a Rat Model.
1/2015	Development and validation of a biomarker for diarrhea-predominant irritable bowel syndrome in human subjects.
10/2012	Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome.
9/2011	Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for post-infectious IBS.

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Mark Pimentel Research Topics

Disease

42	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 06/2021 - 12/2002
20	Constipation 01/2022 - 01/2003
15	Diarrhea 01/2021 - 01/2003
6	Abdominal Pain (Pain, Abdominal) 01/2020 - 01/2011
5	Infections 01/2022 - 05/2015
5	Gastroenteritis 01/2020 - 05/2012
4	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2017 - 01/2003
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 01/2018
2	Severe Acute Respiratory Syndrome 01/2022 - 01/2021
2	Dysbiosis 01/2022 - 01/2020
2	Flatulence 01/2014 - 08/2010
2	Gastroesophageal Reflux (GERD) 11/2010 - 08/2010
2	Lactose Intolerance (Intolerance, Lactose) 08/2010 - 12/2003
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Cytokine Release Syndrome 09/2021
1	Systemic Scleroderma (Systemic Sclerosis) 06/2021
1	COVID-19 01/2021
1	Critical Illness (Critically Ill) 01/2021
1	Malnutrition (Nutritional Deficiencies) 10/2020
1	Inflammation (Inflammations) 01/2020
1	Appendicitis 01/2020
1	Fecal Incontinence 01/2018
1	Dyspepsia (Indigestion) 09/2017
1	Pain (Aches) 09/2017
1	Weight Loss (Weight Reduction) 11/2016
1	Obesity 03/2016
1	Type 2 Diabetes Mellitus (MODY) 05/2012
1	Gastritis 05/2012
1	Peptic Ulcer (Peptic Ulcers) 12/2011
1	Bronchiolitis Obliterans 11/2010
1	Idiopathic Pulmonary Fibrosis 11/2010
1	Celiac Disease (Celiac Sprue) 01/2010
1	Ulcerative Colitis 01/2010

Drug/Important Bio-Agent (IBA)

16	Anti-Bacterial Agents (Antibiotics)IBA 10/2020 - 10/2006
15	Lactulose (Duphalac)FDA LinkGeneric 01/2022 - 12/2002
15	Rifaximin (L 105)FDA Link 01/2021 - 10/2006
8	VinculinIBA 01/2022 - 01/2015
8	Biomarkers (Surrogate Marker)IBA 06/2021 - 01/2004
7	cytolethal distending toxinIBA 10/2020 - 09/2011
6	AntibodiesIBA 01/2022 - 01/2015
6	HydrogenIBA 01/2020 - 01/2003
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 03/2016
3	Proton Pump InhibitorsIBA 07/2016 - 08/2010
3	Neomycin FDA LinkGeneric 06/2014 - 08/2006
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2020
2	CarbohydratesIBA 09/2017 - 01/2017
2	Pharmaceutical PreparationsIBA 09/2012 - 04/2012
2	GasesIBA 08/2010 - 01/2003
2	Lactose FDA LinkGeneric 08/2010 - 12/2003
1	Interleukin-8 (Interleukin 8)IBA 01/2022
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Progesterone FDA LinkGeneric 01/2022
1	Testosterone (Sustanon)FDA Link 01/2022
1	CytokinesIBA 09/2021
1	Chloride Channel AgonistsIBA 01/2021
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 01/2021
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2021
1	acceleratory factor from growth hormone (AcG)IBA 01/2021
1	AutoantibodiesIBA 10/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020
1	VitaminsIBA 10/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Bile Acids and Salts (Bile Acids)IBA 01/2020
1	ParaffinIBA 01/2020
1	Formaldehyde (Formol)FDA Link 01/2020
1	Phenobarbital (Luminal)FDA Link 09/2017
1	LDL CholesterolIBA 03/2016
1	Insulin (Novolin)FDA Link 03/2016
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2016
1	LactonesIBA 01/2016
1	EnzymesIBA 01/2016
1	RifamycinsIBA 03/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013
1	Immunoglobulin E (IgE)IBA 05/2012
1	Lubiprostone FDA Link 04/2012
1	alosetron (Lotronex)FDA Link 04/2012
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 04/2012
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 04/2012
1	Antidepressive Agents (Antidepressants)IBA 01/2012
1	Triggering Receptor Expressed on Myeloid Cells-1IBA 12/2011
1	AcidsIBA 11/2010
1	Narcotics (Narcotic Analgesics)IBA 01/2010
1	tegaserod (Zelnorm)FDA Link 06/2009
1	Erythromycin (Erycette)FDA LinkGeneric 06/2009
1	Serotonin (5 Hydroxytryptamine)IBA 01/2004

Therapy/Procedure

9	Therapeutics 01/2021 - 01/2007
3	Aftercare (After-Treatment) 06/2014 - 06/2009
1	Appendectomy 01/2020
1	Diet Therapy (Therapy, Diet) 01/2019
1	Restorative Proctocolectomy 01/2018
1	Bariatric Surgery 11/2016
1	Drug Therapy (Chemotherapy) 04/2012
1	Tonsillectomy 11/2011
1	Lung Transplantation 11/2010